TNF-inhibition with etanercept for graft versus host disease prevention in high risk HCT: Lower TNFR1 levels correlate with better outcomes

PURPOSE: Graft-versus-host disease (GVHD) causes most non-relapse mortality (NRM) following alternative donor (unrelated and mismatched related) hematopoietic cell transplant (HCT). We previously showed that increases in day +7 TNF-receptor-1 (TNFR1) ratios (post-transplant day +7/pre-transplant bas...

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Autors principals: Choi, Sung W., Stiff, Patrick, Cooke, Kenneth, Ferrara, James L.M., Braun, Thomas, Kitko, Carrie, Reddy, Pavan, Yanik, Gregory, Mineishi, Shin, Paczesny, Sophie, Hanauer, David, Pawarode, Attaphol, Peres, Edward, Rodriguez, Tulio, Smith, Scott, Levine, John E.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443302/
https://ncbi.nlm.nih.gov/pubmed/22469883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2012.03.013
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