Cryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier

Cryptococcus neoformans (C. neoformans) penetration into the central nervous system (CNS) requires traversal of the blood-brain barrier that is composed of a single layer of human brain microvascular endothelial cells (HBMEC), but the underlying mechanisms of C. neoformans traversal remain incomplet...

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Detalhes bibliográficos
Main Authors: Maruvada, Ravi, Zhu, Longkun, Pearce, Donna, Zheng, Yi, Perfect, John, Kwon-Chung, Kyung J., Kim, Kwang Sik
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443264/
https://ncbi.nlm.nih.gov/pubmed/22646320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2012.01819.x
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