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Down-weighting overlapping genes improves gene set analysis

BACKGROUND: The identification of gene sets that are significantly impacted in a given condition based on microarray data is a crucial step in current life science research. Most gene set analysis methods treat genes equally, regardless how specific they are to a given gene set. RESULTS: In this wor...

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Detalhes bibliográficos
Main Authors: Tarca, Adi Laurentiu, Draghici, Sorin, Bhatti, Gaurav, Romero, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443069/
https://ncbi.nlm.nih.gov/pubmed/22713124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-136
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