Elevated Protein Kinase C-delta Contributes to Aneurysm Pathogenesis through Stimulation of Apoptosis and Inflammatory Signaling

OBJECTIVE: Apoptosis of smooth muscle cells (SMCs) is a prominent pathological characteristic of Abdominal Aortic Aneurysm (AAA). We have previously shown that SMC apoptosis stimulates proinflammatory signaling in a mouse model of AAA. Here, we test whether Protein Kinase C-delta (PKCδ), an apoptoti...

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Detalhes bibliográficos
Main Authors: Morgan, Stephanie, Yamanouchi, Dai, Harberg, Calvin, Wang, Qiwei, Keller, Melissa, Si, Yi, Burlingham, William, Seedial, Stephen, Lengfeld, Justin, Liu, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442600/
https://ncbi.nlm.nih.gov/pubmed/22879584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.255661
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