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High Conformational Stability of Secreted Eukaryotic Catalase-peroxidases: ANSWERS FROM FIRST CRYSTAL STRUCTURE AND UNFOLDING STUDIES

Catalase-peroxidases (KatGs) are bifunctional heme enzymes widely spread in archaea, bacteria, and lower eukaryotes. Here we present the first crystal structure (1.55 Å resolution) of an eukaryotic KatG, the extracellular or secreted enzyme from the phytopathogenic fungus Magnaporthe grisea. The hem...

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Autores principales: Zámocký, Marcel, García-Fernández, Queralt, Gasselhuber, Bernhard, Jakopitsch, Christa, Furtmüller, Paul G., Loewen, Peter C., Fita, Ignacio, Obinger, Christian, Carpena, Xavi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442556/
https://ncbi.nlm.nih.gov/pubmed/22822072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.384271
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