A Novel Hydrogen Sulfide-releasing N-Methyl-d-Aspartate Receptor Antagonist Prevents Ischemic Neuronal Death

Physiological levels of H(2)S exert neuroprotective effects, whereas high concentrations of H(2)S may cause neurotoxicity in part via activation of NMDAR. To characterize the neuroprotective effects of combination of exogenous H(2)S and NMDAR antagonism, we synthesized a novel H(2)S-releasing NMDAR...

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Bibliographische Detailangaben
Hauptverfasser: Marutani, Eizo, Kosugi, Shizuko, Tokuda, Kentaro, Khatri, Ashok, Nguyen, Rebecca, Atochin, Dmitriy N., Kida, Kotaro, Van Leyen, Klaus, Arai, Ken, Ichinose, Fumito
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Neurobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442543/
https://ncbi.nlm.nih.gov/pubmed/22815476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374124
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