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Catalytic Convergence of Manganese and Iron Lipoxygenases by Replacement of a Single Amino Acid
Lipoxygenases (LOXs) contain a hydrophobic substrate channel with the conserved Gly/Ala determinant of regio- and stereospecificity and a conserved Leu residue near the catalytic non-heme iron. Our goal was to study the importance of this region (Gly(332), Leu(336), and Phe(337)) of a lipoxygenase w...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442510/ https://ncbi.nlm.nih.gov/pubmed/22822060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.364331 |
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