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Interplay between MEK-ERK signaling, cyclin D1, and cyclin-dependent kinase 5 regulates cell cycle reentry and apoptosis of neurons

In response to neurotoxic signals, postmitotic neurons make attempts to reenter the cell cycle, which results in their death. Although several cell cycle proteins have been implicated in cell cycle–related neuronal apoptosis (CRNA), the molecular mechanisms that underlie this important event are poo...

詳細記述

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書誌詳細
主要な著者: Modi, Prashant Kumar, Komaravelli, Narayana, Singh, Neha, Sharma, Pushkar
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442418/
https://ncbi.nlm.nih.gov/pubmed/22833568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-02-0125
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