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Interplay between MEK-ERK signaling, cyclin D1, and cyclin-dependent kinase 5 regulates cell cycle reentry and apoptosis of neurons

In response to neurotoxic signals, postmitotic neurons make attempts to reenter the cell cycle, which results in their death. Although several cell cycle proteins have been implicated in cell cycle–related neuronal apoptosis (CRNA), the molecular mechanisms that underlie this important event are poo...

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Bibliografiska uppgifter
Huvudupphovsmän: Modi, Prashant Kumar, Komaravelli, Narayana, Singh, Neha, Sharma, Pushkar
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442418/
https://ncbi.nlm.nih.gov/pubmed/22833568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-02-0125
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