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Quiescent fibroblasts are protected from proteasome inhibition–mediated toxicity
Proteasome inhibition is used as a treatment strategy for multiple types of cancers. Although proteasome inhibition can induce apoptotic cell death in actively proliferating cells, it is less effective in quiescent cells. In this study, we used primary human fibroblasts as a model system to explore...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442405/ https://ncbi.nlm.nih.gov/pubmed/22875985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-03-0192 |
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