Quiescent fibroblasts are protected from proteasome inhibition–mediated toxicity

Proteasome inhibition is used as a treatment strategy for multiple types of cancers. Although proteasome inhibition can induce apoptotic cell death in actively proliferating cells, it is less effective in quiescent cells. In this study, we used primary human fibroblasts as a model system to explore...

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Main Authors: Legesse-Miller, Aster, Raitman, Irene, Haley, Erin M., Liao, Albert, Sun, Lova L., Wang, David J., Krishnan, Nithya, Lemons, Johanna M. S., Suh, Eric J., Johnson, Elizabeth L., Lund, Benjamin A., Coller, Hilary A.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442405/
https://ncbi.nlm.nih.gov/pubmed/22875985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-03-0192
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