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Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors

Cellular differentiation and lineage commitment are considered to be robust and irreversible processes during development. Recent work has shown that mouse and human fibroblasts can be reprogrammed to a pluripotent state with a combination of four transcription factors. We hypothesized that combinat...

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Autori principali: Ishii, Ryuga, Kami, Daisuke, Toyoda, Masashi, Makino, Hatsune, Gojo, Satoshi, Ishii, Toshiharu, Umezawa, Akihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442400/
https://ncbi.nlm.nih.gov/pubmed/22833560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-10-0869
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