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Hydrophobic Oxime Ethers: A Versatile Class of pDNA and siRNA Transfection Lipids

The manipulation of cationic lipid structure to increase polynucleotide binding and delivery properties while also minimizing associated cytotoxicity has been a principal strategy for developing next-generation transfection agents. The polar (DNA-binding) and hydrophobic domains of transfection lipi...

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Autors principals: Biswas, Souvik, Knipp, Ralph J., Gordon, Laura E., Nandula, Seshagiri R., Gorr, Sven-Ulrik, Clark, Geoffrey J., Nantz, Michael H.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442363/
https://ncbi.nlm.nih.gov/pubmed/21882348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100259
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