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DSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesis
Most common genetic factors known to cause intellectual disability are Down syndrome and Fragile X syndrome. However, the underlying cellular and molecular mechanisms of intellectual disability remain unclear. Recently, dendritic spine dysmorphogenesis and impaired local protein synthesis are posite...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Nature Publishing Group
2012
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442268/ https://ncbi.nlm.nih.gov/pubmed/22863780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.190 |
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