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DSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesis

Most common genetic factors known to cause intellectual disability are Down syndrome and Fragile X syndrome. However, the underlying cellular and molecular mechanisms of intellectual disability remain unclear. Recently, dendritic spine dysmorphogenesis and impaired local protein synthesis are posite...

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Hlavní autoři: Wang, Wei, Zhu, John Z, Chang, Karen T, Min, Kyung-Tai
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442268/
https://ncbi.nlm.nih.gov/pubmed/22863780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.190
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