MOZ Regulates the Tbx1 Locus, and Moz Mutation Partially Phenocopies DiGeorge Syndrome

DiGeorge syndrome, caused by a 22q11 microdeletion or mutation of the TBX1 gene, varies in severity greatly, even among monozygotic twins. Epigenetic phenomena have been invoked to explain phenotypic differences in individuals of identical genetic composition, although specific chromatin modificatio...

Full description

Saved in:
Bibliographic Details
Main Authors: Voss, Anne K., Vanyai, Hannah K., Collin, Caitlin, Dixon, Mathew P., McLennan, Tamara J., Sheikh, Bilal N., Scambler, Peter, Thomas, Tim
Format: Artigo
Language:Inglês
Published: Cell Press 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442180/
https://ncbi.nlm.nih.gov/pubmed/22921202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.07.010
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items