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Cdc6 Chromatin Affinity Is Unaffected by Serine-54 Phosphorylation, S-Phase Progression, and Overexpression of Cyclin A

Ectopically expressed Cdc6 is translocated from the nucleus during S phase in a cyclin A-Cdk2-dependent process, suggesting that reinitiation of DNA replication is prevented by removal of phosphorylated Cdc6 from chromatin after origin firing. However, whether endogenous Cdc6 translocates during S p...

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Detalhes bibliográficos
Main Authors: Alexandrow, Mark G., Hamlin, Joyce L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC344196/
https://ncbi.nlm.nih.gov/pubmed/14749377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1614-1627.2004
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