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A Cell Culture Adapted HCV JFH1 Variant That Increases Viral Titers and Permits the Production of High Titer Infectious Chimeric Reporter Viruses

The unique properties of the hepatitis C virus (HCV) JFH1 isolate have made it possible to produce and study HCV in an infectious cell culture system. However, relatively low virus titers restrict some of the uses of this system and preparing infectious chimeric reporter viruses have been difficult....

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Autori principali: Liu, Shuanghu, Xiao, Li, Nelson, Cassie, Hagedorn, Curt
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441746/
https://ncbi.nlm.nih.gov/pubmed/23028707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044965
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