Widespread uncoupling between transcriptome and translatome variations after a stimulus in mammalian cells

BACKGROUND: The classical view on eukaryotic gene expression proposes the scheme of a forward flow for which fluctuations in mRNA levels upon a stimulus contribute to determine variations in mRNA availability for translation. Here we address this issue by simultaneously profiling with microarrays th...

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Библиографические подробности
Главные авторы: Tebaldi, Toma, Re, Angela, Viero, Gabriella, Pegoretti, Ilaria, Passerini, Andrea, Blanzieri, Enrico, Quattrone, Alessandro
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441405/
https://ncbi.nlm.nih.gov/pubmed/22672192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-220
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