Reliability of KRAS mutation testing in metastatic colorectal cancer patients across five laboratories

BACKGROUND: Mutations in the KRAS gene are associated with poor response to epidermal growth factor receptor inhibitors used in the treatment of metastatic colorectal cancer. Factors influencing KRAS test results in tumor specimens include: tumor heterogeneity, sample handling, slide preparation, te...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Feigelson, Heather Spencer, Goddard, Katrina AB, Johnson, Monique A, Funk, Kellyan C, Rahm, Alanna Kulchak, Kauffman, Tia L, Chitale, Dhananjay A, Le Marchand, Loic, Richards, C Sue
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Short Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441241/
https://ncbi.nlm.nih.gov/pubmed/22534075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-196
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