Glibenclamide Administration Attenuates Infarct Volume, Hemispheric Swelling, and Functional Impairments following Permanent Focal Cerebral Ischemia in Rats

Studies from a single laboratory have shown that in rodent models of permanent stroke, administration of the sulfonylurea glibenclamide (Glib) is highly effective in reducing edema, mortality, and lesion volume. The Stroke Therapy Academic Industry Roundtable (STAIR) recommends that new acute treatm...

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Autori principali: Wali, Bushra, Ishrat, Tauheed, Atif, Fahim, Hua, Fang, Stein, Donald G., Sayeed, Iqbal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440943/
https://ncbi.nlm.nih.gov/pubmed/22988544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/460909
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