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Response Surface Optimization of Sustained Release Metformin-Hydrochloride Matrix Tablets: Influence of Some Hydrophillic Polymers on the Release

The aim of the present work was designed to develop a model-sustained release matrix tablet formulation for Metformin hydrochloride using wet granulation technique. In the present study the formulation design was employed to statistically optimize different parameters of Metformin hydrochloride tabl...

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Autors principals: Roy, Amitava, Roy, Kalpana, Roy, Sarbani, Deb, Jyotirmoy, Ghosh, Amitava, Ali, Kazi Asraf
Format: Artigo
Idioma:Inglês
Publicat: International Scholarly Research Network 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440925/
https://ncbi.nlm.nih.gov/pubmed/22988527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/364261
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