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Long-term protective effects of the angiotensin receptor blocker telmisartan on epirubicin-induced inflammation, oxidative stress and myocardial dysfunction

Chronic inflammation, oxidative stress and the renin-angiotensin system (RAS) play a significant role in chemotherapy-induced cardiotoxicity (CTX). Telmisartan (TEL), an antagonist of the angiotensin II type-1 receptor, was found to reduce anthracycline (ANT)-induced CTX. We carried out a phase II p...

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書誌詳細
主要な著者: DESSÌ, MARIELE, PIRAS, ALESSANDRA, MADEDDU, CLELIA, CADEDDU, CHRISTIAN, DEIDDA, MARTINO, MASSA, ELENA, ANTONI, GIORGIA, MANTOVANI, GIOVANNI, MERCURO, GIUSEPPE
フォーマット: Artigo
言語:Inglês
出版事項: D.A. Spandidos 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440822/
https://ncbi.nlm.nih.gov/pubmed/22977612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2011.305
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