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Pre-clinical drug tests in the mdx mouse as a model of dystrophinopathies: an overview
Duchenne muscular dystrophy is a lethal X-linked muscle disease affecting 1/3500 live male birth. It results from defects in the subsarcolemmal protein dystrophin, a component of the dystrophinglycoprotein complex (DGC) which links the intracellular cytoskeleton to the extracellular matrix. The abse...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Pacini Editore SpA
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3440805/ https://ncbi.nlm.nih.gov/pubmed/22655516 |
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