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Accuracy of genotyping using the TaqMan PCR assay for single nucleotide polymorphisms responsible for thiopurine sensitivity in Japanese patients with inflammatory bowel disease

Thiopurine drugs are the most common drugs used to maintain clinical remission in inflammatory bowel disease (IBD). Three single-nucleotide polymorphisms (SNPs), TPMT A719G (rs1142345), inosine triphosphate pyrophosphatase (ITPase) C94A (rs1127354) and multidrug resistance protein 4 MRP4 G2269A (rs3...

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Detalhes bibliográficos
Main Authors: OSAKI, RIE, IMAEDA, HIROTSUGU, BAN, HIROMITSU, AOMATSU, TOMOKI, BAMBA, SHIGEKI, TSUJIKAWA, TOMOYUKI, SASAKI, MASAYA, FUJIYAMA, YOSHIHIDE, ANDOH, AKIRA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440725/
https://ncbi.nlm.nih.gov/pubmed/22977575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2011.287
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