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An age-dependent reversal in the protective capacities of JNK signaling shortens Caenorhabditis elegans lifespan

Stress-activated protein kinase (SAPK) pathways are evolutionarily conserved signaling modules that orchestrate protective responses to adverse environmental conditions. However, under certain conditions, their activation can be deleterious. Thus, activation of the c-Jun N-terminal kinase (JNK) SAPK...

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Detalhes bibliográficos
Main Authors: Twumasi-Boateng, Kwame, Wang, Tim W, Tsai, Linda, Lee, Kuang-Hui, Salehpour, Ali, Bhat, Sudarshan, Tan, Man-Wah, Shapira, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440580/
https://ncbi.nlm.nih.gov/pubmed/22554143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00829.x
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