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An age-dependent reversal in the protective capacities of JNK signaling shortens Caenorhabditis elegans lifespan
Stress-activated protein kinase (SAPK) pathways are evolutionarily conserved signaling modules that orchestrate protective responses to adverse environmental conditions. However, under certain conditions, their activation can be deleterious. Thus, activation of the c-Jun N-terminal kinase (JNK) SAPK...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3440580/ https://ncbi.nlm.nih.gov/pubmed/22554143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00829.x |
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