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Low-Dose Rapamycin Treatment Increases the Ability of Human Regulatory T Cells to Inhibit Transplant Arteriosclerosis In Vivo

Regulatory T cells (T(reg)) are currently being tested in clinical trials as a potential therapy in cell and solid organ transplantation. The immunosuppressive drug rapamycin has been shown to preferentially promote T(reg) expansion. Here, we hypothesized that adjunctive rapamycin therapy might pote...

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Autors principals: Hester, J, Schiopu, A, Nadig, S N, Wood, K J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Inc 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440570/
https://ncbi.nlm.nih.gov/pubmed/22500984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04065.x
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