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Legionella pneumophila Type II Protein Secretion Promotes Virulence in the A/J Mouse Model of Legionnaires' Disease Pneumonia

Legionella pneumophila, the gram-negative agent of Legionnaires' disease, possesses type IV pili and a type II protein secretion (Lsp) system, both of which are dependent upon the PilD prepilin peptidase. By analyzing multiple pilD mutants and various types of Lsp mutants as well as performing...

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Autori principali: Rossier, Ombeline, Starkenburg, Shawn R., Cianciotto, Nicholas P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC344012/
https://ncbi.nlm.nih.gov/pubmed/14688110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.1.310-321.2004
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