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O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability
The posttranslational modification of eukaryotic intracellular proteins by O-linked N-acetylglucosamine (O-GlcNAc) monosaccharides is essential for cell viability, yet its precise functional roles are largely unknown. O-GlcNAc transferase utilizes UDP-GlcNAc, the end product of hexosamine biosynthes...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC34401/ https://ncbi.nlm.nih.gov/pubmed/11371615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111099998 |
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