Maternal Exposure to Polycyclic Aromatic Hydrocarbons and 5’-CpG Methylation of Interferon-γ in Cord White Blood Cells

Background: Maternal factors are implicated in the onset of childhood asthma. Differentiation of naïve CD4(+) T lymphocytes into pro-allergic T-helper 2 cells induces interleukin (IL)4 expression and inhibits interferon (IFN)γ expression accompanied by concordant methylation changes in the promoters...

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Main Authors: Tang, Wan-yee, Levin, Linda, Talaska, Glenn, Cheung, Yuk Yin, Herbstman, Julie, Tang, Deliang, Miller, Rachel L, Perera, Frederica, Ho, Shuk-Mei
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2012
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440069/
https://ncbi.nlm.nih.gov/pubmed/22562770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1103744
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