In Vivo Selection of CD4(+) T Cells Transduced with a Gamma-Retroviral Vector Expressing a Single-Chain Intrabody Targeting HIV-1 Tat

We evaluated the potential of an anti–human immunodeficiency virus (HIV) Tat intrabody (intracellular antibody) to promote the survival of CD4(+) cells after chimeric simian immunodeficiency virus (SIV)/HIV (SHIV) infection in rhesus macaques. Following optimization of stimulation and transduction c...

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Detalhes bibliográficos
Main Authors: Braun, Stephen E., Taube, Ran, Zhu, Quan, Wong, Fay Eng, Murakami, Akikazu, Kamau, Erick, Dwyer, Markryan, Qiu, Gang, Daigle, Janet, Carville, Angela, Johnson, R. Paul, Marasco, Wayne A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440024/
https://ncbi.nlm.nih.gov/pubmed/22734618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.184
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