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How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T–product complexes

Exonucleases are key enzymes in the maintenance of genome stability, processing of immature RNA precursors and degradation of unnecessary nucleic acids. However, it remains unclear how exonucleases digest nucleic acids to generate correct end products for next-step processing. Here we show how the e...

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Hlavní autoři: Hsiao, Yu-Yuan, Duh, Yulander, Chen, Yi-Ping, Wang, Yi-Ting, Yuan, Hanna S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439924/
https://ncbi.nlm.nih.gov/pubmed/22718982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks548
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