LRPPRC/SLIRP suppresses PNPase-mediated mRNA decay and promotes polyadenylation in human mitochondria

In human mitochondria, 10 mRNAs species are generated from a long polycistronic precursor that is transcribed from the heavy chain of mitochondrial DNA, in theory yielding equal copy numbers of mRNA molecules. However, the steady-state levels of these mRNAs differ substantially. Through absolute qua...

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Hlavní autoři: Chujo, Takeshi, Ohira, Takayuki, Sakaguchi, Yuriko, Goshima, Naoki, Nomura, Nobuo, Nagao, Asuteka, Suzuki, Tsutomu
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439899/
https://ncbi.nlm.nih.gov/pubmed/22661577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks506
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