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Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone

Natural RNAs, especially tRNAs, are extensively modified to tailor structure and function diversities. Uracil is the most modified nucleobase among all natural nucleobases. Interestingly, >76% of uracil modifications are located on its 5-position. We have investigated the natural 5-methoxy (5-O-C...

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Bibliografiska uppgifter
Huvudupphovsmän: Sheng, Jia, Zhang, Wen, Hassan, Abdalla E. A., Gan, Jianhua, Soares, Alexei S., Geng, Song, Ren, Yi, Huang, Zhen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439885/
https://ncbi.nlm.nih.gov/pubmed/22641848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks426
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