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A new strategy to reduce allelic bias in RNA-Seq readmapping
Accurate estimation of expression levels from RNA-Seq data entails precise mapping of the sequence reads to a reference genome. Because the standard reference genome contains only one allele at any given locus, reads overlapping polymorphic loci that carry a non-reference allele are at least one mis...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3439884/ https://ncbi.nlm.nih.gov/pubmed/22584625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks425 |
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