लोड हो रहा है...
Bulged DNA substrates for identifying poxvirus resolvase inhibitors
Resolvase enzymes that cleave DNA four-way (Holliday) junctions are required for poxvirus replication, but clinically useful inhibitors have not been developed. Here, we report an assay for resolvase cleavage activity based on fluorescence polarization (FP) for high-throughput screening and mechanis...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3439875/ https://ncbi.nlm.nih.gov/pubmed/22581770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks325 |
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