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Diverse Developmental Disorders from The One Ring: Distinct Molecular Pathways Underlie the Cohesinopathies

The multi-subunit protein complex, cohesin, is responsible for sister chromatid cohesion during cell division. The interaction of cohesin with DNA is controlled by a number of additional regulatory proteins. Mutations in cohesin, or its regulators, cause a spectrum of human developmental syndromes k...

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Detalhes bibliográficos
Main Authors: Horsfield, Julia A., Print, Cristin G., Mönnich, Maren
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439829/
https://ncbi.nlm.nih.gov/pubmed/22988450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00171
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