Inhibition of CD1 Expression in Human Dendritic Cells during Intracellular Infection with Leishmania donovani

Dendritic cells can initiate antimicrobial responses by CD1-mediated presentation of pathogen-derived glycolipids. We show that the protozoan Leishmania donovani inhibits CD1 expression and prevents activation of CD1-restricted T cells by dendritic cells. Evasion of presentation by CD1 may represent...

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Detalhes bibliográficos
Main Authors: Amprey, Joseph L., Späth, Gerald F., Porcelli, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC343976/
https://ncbi.nlm.nih.gov/pubmed/14688141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.1.589-592.2004
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