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Complement and dysbiosis in periodontal disease

Signaling crosstalk between complement and Toll-like receptors (TLRs) normally serves to coordinate host immunity. However, the periodontal bacterium Porphyromonas gingivalis expresses C5 convertase-like enzymatic activity and adeptly exploits complement-TLR crosstalk to subvert host defenses and es...

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Bibliografske podrobnosti
Main Authors: Hajishengallis, George, Lambris, John D.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439646/
https://ncbi.nlm.nih.gov/pubmed/22964237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2012.07.007
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