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Radiosynthesis of [(11)C]SNAP-7941—the first PET-tracer for the melanin concentrating hormone receptor 1 (MCHR1)

The melanin concentrating hormone (MCH) system is a new target to treat human disorders. Our aim was the preparation of the first PET-tracer for the MCHR1. [(11)C]SNAP-7941 is a carbon-11 labeled analog of the published MCHR1 antagonist SNAP-7941. The optimum reaction conditions were 2 min reaction...

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Detalles Bibliográficos
Main Authors: Philippe, C., Schirmer, E., Mitterhauser, M., Shanab, K., Lanzenberger, R., Karanikas, G., Spreitzer, H., Viernstein, H., Wadsak, W.
Formato: Artigo
Idioma:Inglês
Publicado: Pergamon Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439630/
https://ncbi.nlm.nih.gov/pubmed/22858577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2012.07.010
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