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Distal-less 3 haploinsufficiency results in elevated placental oxidative stress and altered fetal growth kinetics in the mouse
Distal-less 3 (Dlx3)(-/-) mice die at E9.5 presumably due to an abnormal placental phenotype including reduced placental vasculature and secretion of placental growth factor. To examine the role of Dlx3 specifically within the epiblast, Dlx3 conditional knockout mice were generated using an epiblast...
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Hoofdauteurs: | , , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2012
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3439566/ https://ncbi.nlm.nih.gov/pubmed/22819041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2012.06.018 |
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