Neisseria meningitidis Lipooligosaccharide Structure-Dependent Activation of the Macrophage CD14/Toll-Like Receptor 4 Pathway

Meningococcal lipopoly(oligo)saccharide (LOS) is a major inflammatory mediator of fulminant meningococcal sepsis and meningitis. Highly purified wild-type meningococcal LOS and LOS from genetically defined mutants of Neisseria meningitidis that contained specific mutations in LOS biosynthesis pathwa...

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Detalhes bibliográficos
Main Authors: Zughaier, Susu M., Tzeng, Yih-Ling, Zimmer, Shanta M., Datta, Anup, Carlson, Russell W., Stephens, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC343956/
https://ncbi.nlm.nih.gov/pubmed/14688118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.1.371-380.2004
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