δ-Catenin Is Genetically and Biologically Associated with Cortical Cataract and Future Alzheimer-Related Structural and Functional Brain Changes

Multiple lines of evidence suggest that specific subtypes of age-related cataract (ARC) and Alzheimer disease (AD) are related etiologically. To identify shared genetic factors for ARC and AD, we estimated co-heritability of quantitative measures of cataract subtypes with AD-related brain MRI traits...

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Autors principals: Jun, Gyungah, Moncaster, Juliet A., Koutras, Carolina, Seshadri, Sudha, Buros, Jacqueline, McKee, Ann C., Levesque, Georges, Wolf, Philip A., St. George-Hyslop, Peter, Goldstein, Lee E., Farrer, Lindsay A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439481/
https://ncbi.nlm.nih.gov/pubmed/22984439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043728
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