Overexpression of SDF-1α Enhanced Migration and Engraftment of Cardiac Stem Cells and Reduced Infarcted Size via CXCR4/PI3K Pathway

Cardiac stem cells (CSCs) can home to the infarcted area and regenerate myocardium. Stromal cell-derived factor-1α/C-X-C chemokine receptor type 4 (SDF-1α/CXCR4) axis is pivotal in inducing CSCs migration. However, the mechanisms remain unclear. This study set out to detect if SDF-1α promotes migrat...

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Detalhes bibliográficos
Main Authors: Wang, Kui, Zhao, Xiaohui, Kuang, Chunyan, Qian, Dehui, Wang, Hang, Jiang, Hong, Deng, Mengyang, Huang, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439464/
https://ncbi.nlm.nih.gov/pubmed/22984452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043922
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