Oxygen Glucose Deprivation in Rat Hippocampal Slice Cultures Results in Alterations in Carnitine Homeostasis and Mitochondrial Dysfunction

Mitochondrial dysfunction characterized by depolarization of mitochondrial membranes and the initiation of mitochondrial-mediated apoptosis are pathological responses to hypoxia-ischemia (HI) in the neonatal brain. Carnitine metabolism directly supports mitochondrial metabolism by shuttling long cha...

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Autori principali: Rau, Thomas F., Lu, Qing, Sharma, Shruti, Sun, Xutong, Leary, Gregory, Beckman, Matthew L., Hou, Yali, Wainwright, Mark S., Kavanaugh, Michael, Poulsen, David J., Black, Stephen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439445/
https://ncbi.nlm.nih.gov/pubmed/22984394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040881
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