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HIF-1 expression is associated with CCL2 chemokine expression in airway inflammatory cells: implications in allergic airway inflammation

BACKGROUND: The pathogenesis of allergic airway inflammation in asthmatic patients is complex and characterized by cellular infiltrates and activity of many cytokines and chemokines. Both the transcription factor hypoxia inducible factor-1 (HIF-1) and chemokine CCL2 have been shown to play pivotal r...

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Autori principali: Baay-Guzman, Guillermina J, Bebenek, Ilona G, Zeidler, Michelle, Hernandez-Pando, Rogelio, Vega, Mario I, Garcia-Zepeda, Eduardo A, Antonio-Andres, Gabriela, Bonavida, Benjamin, Riedl, Marc, Kleerup, Eric, Tashkin, Donald P, Hankinson, Oliver, Huerta-Yepez, Sara
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439306/
https://ncbi.nlm.nih.gov/pubmed/22823210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-13-60
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