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Large conformational changes of the ɛ subunit in the bacterial F(1)F(0) ATP synthase provide a ratchet action to regulate this rotary motor enzyme

The F(1)F(0) ATP synthase is the smallest motor enzyme known. Previous studies had established that the central stalk, made of the γ and ɛ subunits in the F(1) part and c subunit ring in the F(0) part, rotates relative to a stator composed of α(3)β(3)δab(2) during ATP hydrolysis and synthesis. How t...

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Main Authors: Tsunoda, Satoshi P., Rodgers, Andrew J. W., Aggeler, Robert, Wilce, Matthew C. J., Yoshida, Masasuke, Capaldi, Roderick A.
פורמט: Artigo
שפה:Inglês
יצא לאור: The National Academy of Sciences 2001
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC34392/
https://ncbi.nlm.nih.gov/pubmed/11381110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111128098
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