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Single action potentials and subthreshold electrical events imaged in neurons with a novel fluorescent protein voltage probe

Monitoring neuronal electrical activity using fluorescent protein-based voltage sensors has been limited by small response magnitudes and slow kinetics of existing probes. Here we report the development of a novel fluorescent protein voltage sensor, named ArcLight, and derivative probes that exhibit...

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Detalhes bibliográficos
Main Authors: Jin, Lei, Han, Zhou, Platisa, Jelena, Wooltorton, Julian R. A., Cohen, Lawrence B., Pieribone, Vincent A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439164/
https://ncbi.nlm.nih.gov/pubmed/22958819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.06.040
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