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Design of Bioactive Peptides from Naturally Occurring μ-Conotoxin Structures

To date, cone snail toxins (“conotoxins”) are of great interest in the pursuit of novel subtype-selective modulators of voltage-gated sodium channels (Na(v)s). Na(v)s participate in a wide range of electrophysiological processes. Consequently, their malfunctioning has been associated with numerous d...

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Detalhes bibliográficos
Main Authors: Stevens, Marijke, Peigneur, Steve, Dyubankova, Natalia, Lescrinier, Eveline, Herdewijn, Piet, Tytgat, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438967/
https://ncbi.nlm.nih.gov/pubmed/22773842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.375733
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