p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1

Mainly regulated at the transcriptional level, the cellular cyclin-dependent kinase inhibitor, CDKN1A/p21(WAF1) (p21), is a major cell cycle regulator of the response to DNA damage, senescence and tumor suppression. Here, we report that COUP-TF-interacting protein 2 (CTIP2), recruited to the p21 gen...

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Detalhes bibliográficos
Main Authors: Cherrier, T, Suzanne, S, Redel, L, Calao, M, Marban, C, Samah, B, Mukerjee, R, Schwartz, C, Gras, G, Sawaya, BE, Zeichner, SL, Aunis, D, Van Lint, C, Rohr, O
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438893/
https://ncbi.nlm.nih.gov/pubmed/19581932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.193
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