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Zoledronate inhibits phosphate and bone morphogenetic protein 2-induced extracellular calcification of vascular smooth muscle cells in vitro

The aim of this study was to explore the effects of the bisphosphonate zoledronate on calcification induced by inorganic phosphate (Pi) and/or bone morphogenetic protein 2 (BMP-2) and the underlying mechanisms. Primary vascular smooth muscle cells (VSMCs) from rats were treated with 3 mM Pi or 3 mM...

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Bibliografiske detaljer
Main Authors: HU, M.L., HUANG, Y., ZHENG, Z.H., LEI, Y., LIU, R.J., WANG, X.H., LINDHOLM, B., YU, X.Q.
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438660/
https://ncbi.nlm.nih.gov/pubmed/22969979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2012.501
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