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The β(3)-Integrin Ligand of Borrelia burgdorferi is Critical for Infection of Mice but not Ticks

P66 is a Borrelia burgdorferi surface protein with β(3) integrin binding and channel forming activities. In this study, the role of P66 in mammalian and tick infection was examined. B. burgdorferiΔp66 strains were not infectious in wild-type, TLR2(−/−) or MyD88(−/−) deficient mice. Strains with p66...

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Detalhes bibliográficos
Main Authors: Ristow, Laura C., Miller, Halli E., Padmore, Lavinia J., Chettri, Rekha, Salzman, Nita, Caimano, Melissa J., Rosa, Patricia A., Coburn, Jenifer
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438374/
https://ncbi.nlm.nih.gov/pubmed/22758390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08160.x
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