Markedly Enhanced Skeletal Muscle Transfection Achieved by the Ultrasound-Targeted Delivery of Non-Viral Gene Nanocarriers with Microbubbles

Our goal was to enhance ultrasound (US)-targeted skeletal muscle transfection through the use of poly(ethyleneglycol) (PEG)/polyethylenimine (PEI) nanocomplex gene carriers and adjustments to US and microbubble (MB) parameters. C57BL/6 mice received an intravenous infusion of MBs and either “naked”...

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Detalhes bibliográficos
Main Authors: Burke, Caitlin W., Suk, Jung Soo, Kim, Anthony J., Hsiang, Yu-Han J., Klibanov, Alexander L., Hanes, Justin, Price, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438364/
https://ncbi.nlm.nih.gov/pubmed/22800583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.07.005
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